Ethnobotanical survey of medicinal plants used in curing. A textbook of medicinal plants from nigeria is intended to focus further interests on medicinal plants from nigeria. Ogunyemi the village chemist, department of pharmacognosy, faculty of pharmacy, obafemi awolowo university, ileife. Naturally occurring anticancer compounds represent about half of the chemotherapeutic drugs which have been put in the market against cancer until date. These plants possess good immunomodulatry and antioxidant properties leading to anticancer activity. Based on the fact that herbal medicine is a strong component of integrative medicine, this study was conducted to evaluate the anticancer activity of root. Screening of medicinal plants native to kano and jigawa. Medicinal plants, anticancer agents, bioactive compounds. The screening of medicinal plants used locally for the treatment of infectious diseases, can provide a reliable option in the discovery of potent therapeutic compounds. Ethnobotanical survey of medicinal plants used in curing some. The tropical rainforest of which nigeria is a part has been described by sofowora24 as a reservoir. The plants studied were phyllanthus amarus schum and thonn, euphorbia heterophylla linn. They are physiologically active agents in plants and becoming of high interest scientifically for their health benefits 2021 various plants have been investigated for their flavonoid content and how these compounds affect cancer.
Plantderived anticancer agents in clinical use figure 1. A selected number of potential anticancer agents in phytochemicals isolated from some indigenous food and. Sansevieria liberica gerome and labroy agavaceae is a perennial plant widely distributed in tropical africa. In recent years, medicinal plants have attracted huge attention due to their diverse range of biological and therapeutic properties. Ethnobotanical studies of anticancer plants in ogun state. Medicinal plants in nigeria were considered by several researchers gbile9 and iyamabo to form an important component of the natural wealth of the country. A screening of medicinal plants native to kano and jigawa states of northern nigeria, using artemia cysts brine shrimp test. The collected plants were then evaluated for cytoxicity. Many indigenous plants are used in herbal medicine to cure various diseases and heal injuries. In this study we have selected few medicinal plants which show high potency towards the cancer cell line by inhibiting their progression. Mation published in 2012 on plant derived anticancer compounds.
Echoviruses, a serotype of enteroviruses, infect millions of people globally and there is no specific drug treatment or vaccine available for its management. However, there is little or no literature on the anticancer properties of medicinal plants used in ethnomedicine in nigeria. Pdf exploring the nigerian medicinal plants with anticancer. List and uses of medicinal plants in nigeria in 2019 legit. Natural products especially plants have been used for the treatment of various diseases for. Nigerian antimalarial plants and their anticancer potential. Terrestrial plants have been used as medicines in egypt, china, india, and greece from ancient times and an impressive number of modern drugs. Ethnobotanical survey of medicinal plants used in the. The study showed that 325 species and 95 families of medicinal plants were recognized as being used by most of the people in nigeria for the treatment of various common diseases. Herbal and medicinal plants molecules towards treatment of. Medicinal plants are densely distributed in the tropical rainforest zones of the world of which nigeria fall into. Nigeria, depend on herbal medicine to meet their health care needs 10. It is the tradition that is of remarkable contemporary relevance.
It is documented that medicinal herbs have rich anticancer potential, and on the forefront whenever we talk about anticancer remedies, are significant source of synthetic andor herbal origin. Nigerian medicinal plants aspilia africana, bryophyllum pinnatum, garcinia kola, spondias mombim and uvaria chamea are used in herbal medicine to cure diseases, protect and regenerate liver cells, prevent alcoholic liver damage, viral liver damage and toxic liver damage. Plants that are used as traditional medicine represent a relevant pool for selecting plant candidates that may have anticancer properties. The wellresearched writeups by renowned researchers cover a range of topics which include history, practice, and challenges of. Medicinal plants and traditional medicine in africa traditional medicine development for medical and dental primary health care delivery system in africa. Ten medicinal plants used in nigerian ethno medicine were subjected to. Tolu odugbemi, 2008 materia medica, vegetable 628 pages. West african medicinal plants and their phytochemicals with anticancer properties. It is very likely that a phytochemical investigation of the nigerian plant species may yield maytansinoids, as is.
Medicinal plants are playing an important role as a source of effective anticancer agents and it is significant that 60% of currently used anticancer agents are derived from natural sources including plants2. Traditional west african pharmacopeia, plants and derived. Anticancer and antioxidative activities of nigerian traditional. Food and medicinal uses of the source plants have also been described.
Based on the fact that herbal medicine is a strong component of integrative medicine, this study was conducted to evaluate the anticancer activity of root extracts of. Because fungal and human cells are similar at a biochemical level it is often the case that chemical compounds intended for plant defence have an inhibitory effect on human cells. A bioactivity versus ethnobotanical survey of medicinal plants from nigeria, west africa lydia l. Plants, animals, soils, incantationswords, spiritualism. A textbook of medicinal plants in nigeria by tolu odugbemi 628 pages unilag press.
A compiled check list of these plants including their latin names, families, parts used, medicinal uses, and name in different nigerian states is the main purpose of this study. Although several medicines are available in the market to. The present study represents an attempt to document information on the traditional medicinal plants that used in nigeria. The importance of medicinal plants, and the contribution of phytomedicine to the wellbeing of a significant number of the worlds population, has attracted interest from a variety of disciplines 5. In vitro anticancer screening of 24 locally used nigerian medicinal plants saudat adamson fadeyi1,3, olugbeminiyi o fadeyi2,4, adedeji a adejumo5, cosmas okoro2 and elbert lewis myles1 abstract background. Pdf on jan 1, 2018, abdullahi danbaba abdullahi and others published exploring the nigerian medicinal plants with anticancer activities. We have also developed standards of four plants so far in the entire continent but we are taking it one step further by now having nigeria as a country propose ten plants, which have been accepted.
Results obtained from the plants screened indicate that 18 plant extracts of folk medicine exhibited promising cytotoxic activity against. Species were scientifically identified with the aid of the useful plants of west tropical africa6, nigerian weeds4 nigeria trees16 and medicinal plants of nigeria booklet3. In nigeria the plant is used to make a popular beverage known as zobo. Traditionally used anticancer herbs in india article pdf available in journal of medicinal plant research. Page 6 india has one of the richest plant medical traditions in the world. Medicinal plants either single or in combination as a recipe. Medicinal plants are used to address the twin problems of promoting sustainable livelihoods and treatment of numerous illnesses in nigeria. Medicinal plants have been used for thousands of years in folk medicines in asian and african populations and many plants are consumed for their health benefits in developed nations. In vitro and in vivo anticancer activity of root extracts. Pdf phytochemical and anticancer studies on ten medicinal. Seventeen medicinal plants were mentioned and confirmed to possess bioactive constituents responsible for cancer therapy.
Nigeria is richly endowed with indigenous plants, which are used in herbal medicine to cure diseases and heal injuries. Several reports describe that the anticancer activity of medicinal plants is due to the. There chemical compounds are formulated with a view to create effective drugs against cancer. Phytochemical and anticancer studies on ten medicinal plants. Anticancer potential of medicinal plants and their. Cancer is a leading cause of death worldwide, with approximately 17.
In nigeria, over 100 plants are used for the management of malaria, but little is known for their potential role in combatting cancer. Nigeria is a country blessed with a vast flora of medicinal importance and the therapeutic potency of such plants have been demonstrated by several researchers 11, 12. Emeritus professor of chemistry, university of ibadan, ibadan, former director, national institute for pharm. Some efficacious nigerian anticancer herbal remedies joseph ibomeim okogun, phd, dic, fas, faas, frsc, fcsn, fnsp. However, as described in sections 3 to 5, a number of agents are in preclinical development. The traditional healer provides health care services based on culture, religious background, knowledge, attitudes, and beliefs that are prevalent in his community. In vitro cytotoxic activity of medicinal plants from. Qualitative and quantitative phytochemical screening of some. This paper discussed the factors responsible for, different forms of cancer, as well as organs or parts it affect. Natural products discovered from medicinal plants have played an important role in the treatment of cancer. Evidences have been accumulated since ages to demonstrate promising potential of medicinal plants used in various traditional, complementary, and alternative systems especially for cancer treatment. Phytochemical importance of medicinal plants as potential. Phytochemical analysis and medicinal uses of hibiscus sabdariffa. Research and development consultant professor, phytochemistry.
Phytochemical and anticancer studies on ten medicinal plants used in nigeria article pdf available july 2011 with 82 reads how we measure reads. In africa, up to 80% of the population uses traditional medicine, while in industrialized countries the market for herbal medicine is growing steadily. In conclusion this article provides the knowledge about anticancer medicinal plants of foreign origin, which are used by people all over the world. Medicinal plants have been used in the treatment and prevention of some infectious diseases such as. Illness is regarded as having both natural and supernatural causes and. The study examined the medicinal value of forest products in the treatment of cancer in southwest nigeria. Anticancer potential of plants and natural products. A bioactivity versus ethnobotanical survey of medicinal. Qualitative and quantitative phytochemical screening of. In this study, the ethnomedicinal approach was used to select several medicinal plants native to nigeria, on the basis of their local or traditional uses. Exploring the nigerian medicinal plants with anticancer activities. Whole plant extracts ethanol extracted were prepared, coded as plant extract numbers 117, and tested for their potential as anticancer agents.
Molecular modeling of potential anticancer agents from. Many of the medicinal plants, especially in nigeria have been documented 4. In table 1 these plants are listed along with the parts used for the treatment of malaria, the parts used for anticancer studies, bioactive classescompounds, cancer cell types and the proposed mechanisms of action. Herbal medicines in african traditional medicine intechopen. Plants need to defend themselves from attack by microorganisms, in particular fungi, and they do this by producing antifungal chemicals that are toxic to fungi.
Jan 31, 2015 in recent years, medicinal plants have attracted huge attention due to their diverse range of biological and therapeutic properties. The search identified 56 nigerian antimalarial plants that had also been investigated for their anticancer activity. Introduction natural products especially plants have been used for the treatment of various diseases for thousands of years. Exploring the nigerian medicinal plants with anticancer. The effort to find anticancer agents from higher plants was launched by the us national cancer institute nci in 1957. Also it is of significance to exploit novel anticancer drugs from medicinal plants. Preparations of the plant are commonly used across nigeria for the treatment of inflammatory conditions. Flavonoids are from the polyphenolic compounds and constitute a large family of plant secondary metabolites with 10,000 known structures 19. In nigeria, over 100 plants are used for the management of malaria, but little is known for their potential role in combatting. African traditional medicine is a form of holistic health care system organized into three levels of specialty, namely divination, spiritualism, and herbalism. Anticancer potentials of phytochemicals from some indigenous.
This book contains very interesting writeups on medicinal plants, and pictures of medicinal plants. Of over 100 plants used to treat malaria in nigeria, 56 have documented anticancer properties, containing alkaloids, flavonoids, tannins, terpenes, terpenoids, quinones, anthraquinones, saponins, steroids, sterols, organosulfur compounds and other polyphenols as the major bioactive components. Cancer, chemotherapy,cancer cells, natural products, plants, medicinal plants, herbal medicine. An overview of the anticancer properties of some plants. In vitro anticancer screening of 24 locally used nigerian medicinal. Wild lettuce is a widely used medicinal plant used in traditional medicine not only in nigeria but almost every part of the world where it can be found.
Abstract the phytochemical analyses, nutrient value and economic importance of hibiscus sabdariffa commonly known as zobo plant was carried out. The paper also explored some nigerian medicinal plants with anticancer agents. Pdf in vitro cytotoxic activity of medicinal plants from. This study was carried out to investigate the antiviral activities of. Phytochemical analysis and medicinal uses of hibiscus. Many plantderived products have been reported to exhibit potent antitumor activity against several rodent and. Qualitative and quantitative phytochemical screening of six plants used in ethnomedicine in the niger delta region of nigeria was carried out to identify and quantify the bioactive compounds present in these highly medicinal plants. Medicinal plants as potential source of anticancer.
These plants exhibit a wide range of biological and pharmacological activities such as anti cancer, antiinflammatory, diuretic, laxative, antispasmodic, antihypertensive. Table 2 shows the effects of nigerian antimalarial medicinal. An overview of the anticancer properties of some plants used. Pdf ten medicinal plants used in nigerian ethno medicine were subjected to phytochemical and anticancer studies using established. Om prakash, amit kumar, pawan kumar, and ajeet, anticancer potential of plants. The problems of poor selectivity and severe side effects of the available anticancer drugs, have. Fabaceae has the largest number of species 42, followed by asteraceae 22, euphorbiaceae 20, acanthaceae and apocynaceae 12. Jan 01, 2008 this book provides a clear understanding of the link between plants and health, and it is a useful addition to the growing literature on medicinal plants from nigeria. In vitro anticancer screening of 24 locally used nigerian.
In vitro and in vivo anticancer activity of root extracts of. In vitro antiviral activity of twentyseven medicinal. The use of medicinal plants in the treatment of diseases has generated renewed interest in recent times, as herbal preparations are increasingly being used in both human and animal healthcare systems. Screening of medicinal plants native to kano and jigawa states of northern nigeria, using artemia cysts brine shrimp test. Mali and nigeria have created the center of traditional medicine. Seventeen medicinal plants were mentioned and confirmed to possess bioactive constituents responsible for. Diarrhoea is one of the common clinical signs of gastrointestinal disorders caused by both infectious and noninfectious agents and an important livestock debilitating condition. Newman encyclopedia of life support systems eolss reached the stage of general use.
It is the tradition that is of remarkable contemporary relevance for ensuring health security to the teeming millions. It has been used for relaxant and sedative purposes for thousands of years. Invitro and invivo antitumor activity of catharanthus roseus. The importance of medicinal plants, and the contribution of phytomedicine to the wellbeing of a significant number of the worlds population. So far plants have been proved to be a novel source of useful. Evaluating medicinal plants for anticancer activity.
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